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Call for patient organization input

Stickman with megaphone calling for patient organization inputCall for patient organization input on certolizumab pegol (Cimzia®) for psoriatic arthritis

Do you have psoriatic arthritis or care for someone who does? We need your valuable input.

The Common Drug Review (CDR) is currently welcoming patients and their caregivers to provide input to patient organizations on the manufacturer’s submission for certolizumab pegol (Cimzia®) for the treatment of psoriatic arthritis (PsA). Certolizumab pegol is indicated for use in combination with methotrexate for reducing signs and symptoms and inhibiting the progression of structural damage as assessed by X-ray, in adult patients with moderately to severely active psoriatic arthritis who have failed one or more disease-modifying anti-rheumatic drugs (DMARDs).

The CDR is part of the Canadian Agency for Drugs and Technologies in Health (CADTH). The CDR conducts objective, rigorous reviews of the clinical and cost effectiveness of drugs, and provides formulary listing recommendations to the publicly funded drug plans in Canada (except Quebec).

To help them make their recommendations, the CDR accepts input from patient groups, like Arthritis Consumer Experts (ACE). We would like to gather your views and share them with the CDR.

These are the questions they are asking:

  1. What are the psoriatic arthritis related symptoms and problems that impact the patients' day-to-day life and quality of life? For example: what aspects of psoriatic arthritis are more important to control, how does psoriatic arthritis affect day-to-day life, and are there any activities that the patient is not able to do as a result of psoriatic arthritis?
  2. How well are patients managing their psoriatic arthritis with currently available treatments? Examples of the types of information to be included in the answer are:
    • What therapy are patients using for psoriatic arthritis?
    • How effective is current therapy in controlling the common aspects of psoriatic arthritis?
    • Are there adverse effects that are more difficult to tolerate than others?
    • Are there hardships in accessing current therapy?
    • Are there needs, experienced by some or many patients, which are not being met by current therapy?
    • What are these needs?
  3. What challenges do caregivers face in caring for patients with psoriatic arthritis?
    • How do treatments impact on the caregivers' daily routine or lifestyle?
    • Are there challenges in dealing with adverse effects related to current therapy?
  4. Based on no experience with certolizumab pegol for the treatment of psoriatic arthritis, what are the expectations for the medication?
    • Is it expected that the lives of patients will be improved by certolizumab pegol, and how?
    • Is there a particular gap or unmet patient need in current therapy that certolizumab pegol will help alleviate?
    • Would patients be willing to experience serious adverse effects with certolizumab pegol if they experienced other benefits from the medication?
    • How much improvement in the condition would be considered adequate? What other benefits might certolizumab pegol have, for example, fewer hospital visits or less time off work?
  5. What experiences have patients had to date with certolizumab pegol as part of a clinical trial or through a manufacturer's compassionate supply?
    • What positive and negative effects does certolizumab pegol have on the condition?
    • Which symptoms does certolizumab pegol manage better than the existing therapy and which ones does it manage less effectively?
    • Does certolizumab pegol cause adverse effects?
    • Which adverse effects are acceptable and which ones are not?
    • Is certolizumab pegol easier to use?
    • How is certolizumab pegol expected to change a patient's long-term health and wellbeing?

If you live with psoriatic arthritis or care for someone with the disease, please send us your input by Friday, September 19, 2014, so that we may make a submission by the September 22 deadline. Your input will be anonymous.

Please contact us at info@jointhealth.org to provide your input or arrange for a phone interview at 604-974-1366.