A recent journal published in Arthritis & Rheumatology by the Massachusetts General Hospital/Harvard Medical School shows that acute gout attacks occur two times more often during the night and early morning than during the day. The increased risk was seen even among patients with low purine intake in the 24 hours prior to an attack. Purines are specific chemical compounds found in some foods and are broken down into uric acids. A diet rich in purines from certain sources of food can raise uric acid levels in the body, sometimes leading to the onset of gout.
In an interview with HealthDay, study author Dr. Hyon Choi said: “It is speculated that lower body temperature, nighttime dehydration, or a nocturnal dip of cortisol levels may contribute to the risk of gout attacks at night. Despite the possibility of a nighttime link to gout, no study prior to our current investigation has looked at the association between gout attack risk and the time of day.” Continue reading