A recent research from the University of Southampton shows that the arthritis medication, etanarcept (Enbrel®), may slow Alzheimer’s disease. The research was presented at the Alzheimer’s Association International Conference in Denmark last week.
In the small control study, a group of 41 patients exhibiting mild or moderate Alzheimer’s was given either the anti-inflammatory medication etanercept or a placebo every week over a period of six months.
Researchers monitored memory function in patients and found that the efficiency of day-to-day activities and behaviour and the symptoms of those who had taken etanercept did not get any worse. In comparison, the placebo group showed signs of decline in memory function.
In an interview with the Daily Mail, lead researcher, Professor Clive Holmes, said:
Photo courtesy of Stuart Miles with FreeDigitalPhotos.net
Last week, my computer mouse inadvertently hovered over some advertising scrolling along the screen and I was instantly transported to another website.
This is not the first time this has happened, but before I became involved in an investment pitch or a cure for belly fat (both of which I probably could use), I warned myself to be remain vigilant and then repeatedly hit the “back” button until I was safely back on the terra firma of my home page. Continue reading →
Innovation in Action: Annual arthritis conference brings experts from around the globe to share research, improve patient care
The American College of Rheumatology (ACR) and the Association of Rheumatology Health Professionals (ARHP) meet once a year, bringing researchers from around the world together so they may share information and discuss the latest science, research, and treatments in the field of rheumatology. Innovative sessions, groundbreaking science, education that fills knowledge and practice gaps, and hands-on skills training make up some of the activities of the event.
The goals of the annual conference include:
Identifying developments in disease diagnosis and treatments.
Describing potential issues in delivery of care and sharing ideas for solutions.
Summarizing recent research findings.
Using new research data to improve the quality of patient care.
Encouraging research that leads to new treatment protocols.
Arthritis Consumer Experts was at the most recent event, held in October 2013, to represent people living with arthritis and to learn about the latest research findings so we could share them with you. Of particular interest to consumers were two presentations: One was about the current state of osteoarthritis treatment and ways to improve outcomes in the future. The other discussed recent advances in psoriatic arthritis research and how they could be used to effectively identify, diagnose, and treat the disease to improve patients’ quality of life and function. Continue reading →
Ten big drug companies have joined together with the National Institutes of Health (NIH) to accelerate the discovery of new medicines for diseases like alzheimers, diabetes, rheumatoid arthritis and lupus. The project is called the Accelerating Medicines Partnership. Under the five-year agreement, the companies will be sharing scientists, tissue and blood samples, and data. The underlying goal is to help identify targets for new drugs. Continue reading →
Criteria for denosumab (Prolia®) for osteoporosis and tocilizumab (Actemra®) for rheumatoid arthritis updated.
The Yukon recently added two medications to its Drug Formulary: denosumab (Prolia®) for osteoporosis and tocilizumab (Actemra®) for rheumatoid arthritis. Both medications are considered an Exception drug under the Pharmacare (seniors plan) and the Chronic Disease Program, which requires an application for the Formulary Working Group to assess. Continue reading →
Photo courtesy of sscreations at FreeDigitalPhotos.net
I remember an experience I had many years ago as I made the rounds to various doctors trying to find out why I suffered from crippling pain. A neurologist recommended that a shot of cortisone in my spine could be the miraculous cure to put me out of my misery.
Cortisone earned a reputation as a miracle drug when it was first successfully used in 1948 at the Mayo Clinic to treat a rheumatoid arthritis patient whose crippling joints were unfrozen by the drug. Its label as a miracle medication earned its pioneers the Nobel Prize for Medicine. Cortisone may help relieve pain and is commonly given in joints, but there are limits on the frequency of its usage due to adverse side effects, so physicians have to carefully weigh the benefits against the risks.
I gamely agreed to the cortisone injection (at the time, I would have agreed to just about anything) and I received a shot in my lower back after an epidural to deaden my extremities. When the anesthesia wore off, I arose from the bed where I had been for about an hour. The pain was still there, but I was told that there would be a delay of up to a couple of days between the time the injection was administered and when I would start to feel some relief. Needless to say, no solace came and I soldiered on. Several years later, an orthopedic surgeon suggested I undergo cortisone shots in my back for a second time. I still did not have a positive diagnosis for my ankylosing spondylitis (AS), so throwing caution to the wind, I grasped at the carrot. This cortisone shot also did not produce any results, in fact, the pain seemed to worsen and I swore that I would never go that route again (never say never?).
Years later, when the plantar fasciitis in my heel continued over several months with no relief in sight, a podiatrist suggested I consider cortisone injections. With her reassurances that she expected a good outcome, I again took the bait. Good news! The shots worked and the pain disappeared within a few weeks. Another recent flare-up has me thinking—again—that perhaps I should opt for cortisone to get rid of the heel pain (stay tuned).
I have repeatedly questioned my rheumy about the osteoarthritis in my thumbs and the available options to ease that problem. During my last visit, he casually mentioned the possibility of cortisone shots in the base of my thumbs, but he quickly added that any relief would only be temporary and the injections would be quite “uncomfortable.” His lack of confidence sealed the deal for me: no thanks!
Today, cortisone (and its sister prednisone) is used to lessen the symptoms during acute AS flares. For many AS patients, cortisone truly is a miracle drug. Sometimes this option may be a last ditch attempt to gain relief, but for myself, I did not achieve anything near miraculous. Rather, I will just keep hoping for a miracle cure for AS. ~Fran
Have you ever taken cortisone (or prednisone) shots for your AS? Did it have a positive effect?
Health Canada recently approved adalimumab (Humira®) to treat adults with moderate to severe ulcerative colitis (UC) who are unresponsive to conventional therapy.
Adalimumab is currently approved in Canada for the treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), Crohn’s disease (CD), and psoriasis (Ps) in adults. Adalimumab has also been approved to treat polyarticular juvenile idiopathic arthritis (pJIA) in children aged 4 to 17 years and Crohn’s disease in children aged 13 to 17 years. Continue reading →
Photo courtesy of Renjith Krishnan of FreeDigitalPhotos.net
I recently blogged about my decision to take the annual flu vaccine and why I choose to go this route rather than play the odds of contracting this nasty virus. Making the decision is a no-brainer for me because a few years ago I got the flu and after the horrible full-blown symptoms had disappeared within a couple of weeks, I dragged around for another six weeks before I felt well again. Continue reading →
A friend recently told me that she was prescribed medical marijuana to help with her crippling and frequent migraine pain. As a reformed cigarette smoker, she decided against smoking it and instead, brewed the cannabis into a tea. While the resulting infusion only slightly eased her migraine pain, it made her feel groggy and slow (not ‘high’), so she abandoned this option as a viable alternative treatment.
When her mother who suffers from debilitating arthritis came for tea, she sampled the “special brew” and experienced the opposite effect: she became extremely agitated and therefore, declined to accept a second cup. I have another friend who uses marijuana to combat the debilitating effects of chemotherapy treatments; it is baked into bite-sized cookies that help suppress nausea and stimulate appetite. Continue reading →